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Intelligent Synthesis Engine

INTELLIGENT
SYNTHESIS

A specialist AI infrastructure bridging the gap between raw medical data and publication-ready evidence across all therapeutic areas.

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app.mettasensus.com
Dashboard
New Review
Alerts
Multi-Search
AI Screening
PRISMA 2020
Forest Plot
Efficacy of SGLT2 Inhibitors in Heart Failure
145
Included
89
Excluded
12
Maybe
0.87
Cohen κ
Effects of dapagliflozin on HF outcomes...
AI 94%
Include
SGLT2 inhibitors vs placebo in reduced EF...
AI 71%
Maybe
Trusted by researchers at
Harvard Medical
Johns Hopkins
USP
Fiocruz
NHS
By the numbers
0
Tests Passing
Production-grade quality assurance across all modules
0
Databases
0+
Journals Monitored
0
AI Agents

“The only Cochrane-compliant platform with native meta-analysis”

Everything in one platform

REVIEW

Screen thousands of articles in minutes

AI-powered screening with dual-reviewer simulation. Cohen's κ of 0.87 — exceeding human inter-rater reliability.

  • ✓Include / Exclude / Maybe decisions
  • ✓AI Score per article
  • ✓Complete audit trail
  • ✓Cochrane-compliant workflow
All (47)
Include (12)
Exclude (18)
Maybe (7)
Effect of progesterone on preterm birth outcomes
AI 92%
Include
Cervical length measurement in twin pregnancies
AI 61%
Maybe
Antibiotic prophylaxis in labor: a meta-analysis
AI 14%
Exclude
Screening progress47 / 100
StudyI² = 23.4% · p = 0.012
Meis 2003
Fonseca 2007
Hassan 2011
Norman 2016
Pooled
0.52 [0.41–0.65]
0.00.250.500.751.0
SYNTHESIZE

From raw data to publication-ready synthesis

GRADE certainty assessment, forest plots and network meta-analysis — all integrated, all exportable.

  • ✓Forest Plot with I² heterogeneity
  • ✓GRADE calculator (Cochrane Ch. 14)
  • ✓Network meta-analysis with SUCRA
  • ✓Export RevMan + GRADEpro
ALERTS

Never miss a relevant publication again

PICO-aware monitoring across 80 journals. Get notified when new evidence changes your conclusions.

  • ✓80 journals in 8 specialties
  • ✓PICO relevance scoring via AI
  • ✓Daily or weekly email digest
  • ✓Foundation for Living Systematic Reviews
🔔 6 new articles match your PICO
J
NEJM
3 new
J
Lancet
1 new
J
Cochrane Library
2 new
Daily email digest

How it works.

01
Define your question.
BUILD YOUR PICO FRAMEWORK WITH AI ASSISTANCE.
01
Define your question.
BUILD YOUR PICO FRAMEWORK WITH AI ASSISTANCE.
02
Search everywhere at once.
6 DATABASES. ONE QUERY. ZERO DUPLICATES.
02
Search everywhere at once.
6 DATABASES. ONE QUERY. ZERO DUPLICATES.
03
Screen with AI precision.
COHEN'S κ 0.87. FASTER THAN ANY HUMAN TEAM.
03
Screen with AI precision.
COHEN'S κ 0.87. FASTER THAN ANY HUMAN TEAM.
04
Assess and extract.
ROB 2.0, GRADE, DATA EXTRACTION — ALL INTEGRATED.
04
Assess and extract.
ROB 2.0, GRADE, DATA EXTRACTION — ALL INTEGRATED.
05
Synthesize. Publish.
FOREST PLOT, PRISMA 2020, REVMAN EXPORT. DONE.
05
Synthesize. Publish.
FOREST PLOT, PRISMA 2020, REVMAN EXPORT. DONE.

Monitoring the world's leading journals

80 journals across 8 medical specialties

NEJM·Lancet·JAMA·BMJ·Cochrane Library·Nature Medicine·Cell·PLOS Medicine·Annals of Internal Medicine·NEJM Evidence·European Heart Journal·Gut·Brain·Circulation·NEJM·Lancet·JAMA·BMJ·Cochrane Library·Nature Medicine·Cell·PLOS Medicine·Annals of Internal Medicine·NEJM Evidence·European Heart Journal·Gut·Brain·Circulation·

Simple, transparent pricing

Start free. Upgrade when you need more.

MonthlyAnnual
Free
$0/mo
  • ·1 active review
  • ·3 databases
  • ·Basic PRISMA diagram
  • ·BibTeX / RIS export
  • ·Community support
Get started
Most chosen
Pro
$0/mo
  • ·Unlimited reviews
  • ·8 databases
  • ·AI-powered screening
  • ·Forest plot & meta-analysis
  • ·RevMan & GRADEpro export
  • ·Zotero sync
  • ·Email support
Upgrade plan
Team
$0/mo
  • ·Everything in Pro
  • ·Dual screening & conflict resolution
  • ·Real-time collaboration
  • ·Team audit trail
  • ·Team analytics
  • ·Priority support
Upgrade plan
Enterprise
Custom
  • ·Everything in Team
  • ·SSO / SAML (Azure AD, Okta, Google)
  • ·SOC 2 Type II + dedicated instance
  • ·Custom integrations & API
  • ·Dedicated account manager + SLA
Contact Sales

Start free · Upgrade any time · Enterprise available on request

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🔒SOC 2 compliant📖Cochrane-compliant🇧🇷Built in Brazil
MettaSensus

Clinical Evidence Infrastructure for modern systematic review teams.

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